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Peroxidative aggregation of α-synuclein requires tyrosines

α-Synuclein is the main component of the intracellular protein aggregates in neurons of patients with Parkinson’s disease. The occurrence of the disease is associated with oxidative damage. Although it is known that peroxidative chemistry leads to the aggregation of α-synuclein in vitro, the specifi...

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Autori principali: Olteanu, Alina, Pielak, Gary J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286587/
https://ncbi.nlm.nih.gov/pubmed/15459341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04947204
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