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Optimal bundling of transmembrane helices using sparse distance constraints

We present a two-step approach to modeling the transmembrane spanning helical bundles of integral membrane proteins using only sparse distance constraints, such as those derived from chemical cross-linking, dipolar EPR and FRET experiments. In Step 1, using an algorithm, we developed, the conformati...

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Detalles Bibliográficos
Main Authors: Sale, Ken, Faulon, Jean-Loup, Gray, Genetha A., Schoeniger, Joseph S., Young, Malin M.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286557/
https://ncbi.nlm.nih.gov/pubmed/15340162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04781504
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