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Quantification of helix–helix binding affinities in micelles and lipid bilayers

A theoretical approach for estimating association free energies of α-helices in nonpolar media has been developed. The parameters of energy functions have been derived from ΔΔG values of mutants in water-soluble proteins and partitioning of organic solutes between water and nonpolar solvents. The pr...

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Autors principals: Lomize, Andrei L., Pogozheva, I.D., Mosberg, H.I.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286553/
https://ncbi.nlm.nih.gov/pubmed/15340167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04850804
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