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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4(+)CD25(–) T cells
CD4(+)CD25(+) regulatory T (T(R)) cells have been described in both humans and mice. In mice, T(R) are thymically derived, and lack of T(R) leads to organ-specific autoimmunity. Recently, the forkhead/winged helix transcription factor, FoxP3, has been shown to be important for the function of T(R) c...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2003
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC228469/ https://ncbi.nlm.nih.gov/pubmed/14597769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319441 |
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