Yeast-Derived Human Immunodeficiency Virus Type 1 p55(gag) Virus-Like Particles Activate Dendritic Cells (DCs) and Induce Perforin Expression in Gag-Specific CD8(+) T Cells by Cross-Presentation of DCs

To evaluate the immunogenicity of human immunodeficiency virus (HIV) type 1 p55(gag) virus-like particles (VLPs) released by budding from yeast spheroplasts, we have analyzed the effects of yeast VLPs on monocyte-derived dendritic cells (DCs). Yeast VLPs were efficiently incorporated into DCs via bo...

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Detalhes bibliográficos
Main Authors: Tsunetsugu-Yokota, Yasuko, Morikawa, Yuko, Isogai, Maya, Kawana-Tachikawa, Ai, Odawara, Takashi, Nakamura, Tetsuya, Grassi, Fernanda, Autran, Brigitte, Iwamoto, Aikichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC228384/
https://ncbi.nlm.nih.gov/pubmed/12970409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.19.10250-10259.2003
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