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Arginine 60 in the ArsC arsenate reductase of E. coli plasmid R773 determines the chemical nature of the bound As(III) product

Arsenic is a ubiquitous environmental toxic metal. Consequently, organisms detoxify arsenate by reduction to arsenite, which is then excreted or sequestered. The ArsC arsenate reductase from Escherichia coli plasmid R773, the best characterized arsenic-modifying enzyme, has a catalytic cysteine, Cys...

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Detalhes bibliográficos
Main Authors: DeMel, Srini, Shi, Jin, Martin, Philip, Rosen, Barry P., Edwards, Brian F.P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2280019/
https://ncbi.nlm.nih.gov/pubmed/15295115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04787204
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