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Analysis of the stability of multimeric proteins by effective ΔG and effective m-values
Analyzing the stability of a multimeric protein is challenging because of the intrinsic difficulty in handling the mathematical model for the folded multimer-unfolded monomer equilibrium. To circumvent this problem, we introduce the concept of effective stability, ΔG(eff) (= −RTlnK(eff)), where K(ef...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2280007/ https://ncbi.nlm.nih.gov/pubmed/15322294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04811004 |
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