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Insulin forms amyloid in a strain-dependent manner: An FT-IR spectroscopic study

The presence of 20% (v/v) ethanol triggers growth of insulin amyloid with distinct infrared spectroscopic features, compared with the fibrils obtained under ambient conditions. Here we report that the two insulin amyloid types behave in the prion strain-like manner regarding seeding specificity and...

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Autors principals: Dzwolak, Wojciech, Smirnovas, Vytautas, Jansen, Ralf, Winter, Roland
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279922/
https://ncbi.nlm.nih.gov/pubmed/15169954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03607204
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