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Polymerization of the SAM domain of MAPKKK Ste11 from the budding yeast: Implications for efficient signaling through the MAPK cascades

The sterile α-motif (SAM) is a protein module ~70 residues long and mainly involved in the protein–protein interactions of cell signaling and transcriptional repression. The SAM domain of the yeast MAPKKK Ste11 has a well-folded dimeric structure in solution. Interestingly, the well-folded dimer of...

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Autors principals: Bhattacharjya, Surajit, Xu, Ping, Chakrapani, Mukundan, Johnston, Linda, Ni, Feng
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279271/
https://ncbi.nlm.nih.gov/pubmed/15689513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041122105
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