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The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22
Treatment of human cells with Type 1 interferons restricts HIV replication. Here we report that the tripartite motif protein TRIM22 is a key mediator. We used transcriptional profiling to identify cellular genes that were induced by interferon treatment and identified TRIM22 as one of the most stron...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279259/ https://ncbi.nlm.nih.gov/pubmed/18389079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000007 |
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