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Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention

Se-methylselenocysteine (MSC) is an organoselenium compound being developed for breast cancer chemoprevention. To characterize MSC toxicity, CD rats received daily gavage doses of 0, 0.5, 1.0, or 2.0 mg/kg/day (0, 3, 6, or 12 mg/m(2)/day), and beagle dogs received daily gavage doses of 0, 0.15, 0.3,...

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Hlavní autoři: Johnson, W.D., Morrissey, R.L., Kapetanovic, I., Crowell, J.A., McCormick, D.L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279231/
https://ncbi.nlm.nih.gov/pubmed/18082924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2007.11.001
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