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Fluorescence Resonance Energy Transfer in Quantum Dot-Protein Kinase Assemblies

In search of viable strategies to identify selective inhibitors of protein kinases, we have designed a binding assay to probe the interactions of human phosphoinositide-dependent protein kinase-1 (PDK1) with potential ligands. Our protocol is based on fluorescence resonance energy transfer (FRET) be...

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Détails bibliographiques
Auteurs principaux: Yildiz, Ibrahim, Gao, Xinxin, Harris, Thomas K., Raymo, Françisco M.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279162/
https://ncbi.nlm.nih.gov/pubmed/18401441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/18081
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