Phosphorylation of Ser(982) in the sodium bicarbonate cotransporter kNBC1 shifts the HCO(3)(−): Na(+) stoichiometry from 3:1 to 2:1 in murine proximal tubule cells

1. Adenosine 3′,5′-cyclic monophosphate (cAMP) modulates proximal tubule sodium and bicarbonate absorption by decreasing the rate of apical Na(+)-H(+) exchange and basolateral sodium bicarbonate efflux, through activation of protein kinase A (PKA). The electrogenic sodium bicarbonate cotransporter k...

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Autores principales: Gross, E, Hawkins, K, Pushkin, A, Sassani, P, Dukkipati, R, Abuladze, N, Hopfer, U, Kurtz, I
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2001
Materias:
Rapid Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278987/
https://ncbi.nlm.nih.gov/pubmed/11744745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.00659.x
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