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Drastic reduction of the slow gate of human muscle chloride channel (ClC-1) by mutation C277S

1. Single channel measurements suggest that the human muscle chloride channel ClC-1 presumably has a double barrelled structure, with a fast single protopore gate and a slow common pore gate similar to that of ClC-0, the chloride channel from Torpedo. The single point mutation C212S has been shown t...

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Autori principali: Accardi, Alessio, Ferrera, Loretta, Pusch, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278749/
https://ncbi.nlm.nih.gov/pubmed/11483705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.00745.x
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