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The Role of Telomere Biology in Bone Marrow Failure and Other Disorders
Telomeres, consisting of nucleotide repeats and a protein complex at chromosome ends, are essential in maintaining chromosomal integrity. Dyskeratosis congenita (DC) is the inherited bone marrow failure syndrome (IBMFS) that epitomizes the effects of abnormal telomere biology. Patients with DC have...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278290/ https://ncbi.nlm.nih.gov/pubmed/18160098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2007.11.002 |
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