Antigen kinetics determines immune reactivity

A current paradigm in immunology is that the strength of T cell responses is governed by antigen dose, localization, and costimulatory signals. This study investigates the influence of antigen kinetics on CD8 T cell responses in mice. A fixed cumulative antigen dose was administered by different sch...

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Bibliographische Detailangaben
Hauptverfasser: Johansen, Pål, Storni, Tazio, Rettig, Lorna, Qiu, Zhiyong, Der-Sarkissian, Ani, Smith, Kent A., Manolova, Vania, Lang, Karl S., Senti, Gabriela, Müllhaupt, Beat, Gerlach, Tilman, Speck, Roberto F., Bot, Adrian, Kündig, Thomas M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278203/
https://ncbi.nlm.nih.gov/pubmed/18362362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706296105
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