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Substrate binding, deprotonation, and selectivity at the periplasmic entrance of the Escherichia coli ammonia channel AmtB

The conduction mechanism of Escherichia coli AmtB, the structurally and functionally best characterized representative of the ubiquitous Amt/Rh family, has remained controversial in several aspects. The predominant view has been that it facilitates the movement of ammonium in its uncharged form as i...

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Detalhes bibliográficos
Main Authors: Javelle, Arnaud, Lupo, Domenico, Ripoche, Pierre, Fulford, Tim, Merrick, Mike, Winkler, Fritz K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278191/
https://ncbi.nlm.nih.gov/pubmed/18362341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711742105
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