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Affinity Manipulation of Surface-conjugated RGD-peptide to Modulate Binding of Liposomes to Activated Platelets

Platelet adhesion, activation and fibrinogen-mediated aggregation are primary events in vascular thrombosis and occlusion. An injectable delivery system that can carry thrombolytics selectively to the sites of active platelet aggregation has immense potential in minimally invasive targeted therapy o...

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Bibliografiske detaljer
Main Authors: Huang, Guofeng, Zhou, Zhongmin, Srinivasan, Rekha, Penn, Marc S, Kottke-Marchant, Kandice, Marchant, Roger E., Gupta, Anirban Sen
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278119/
https://ncbi.nlm.nih.gov/pubmed/18192005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2007.12.015
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