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Affinity Manipulation of Surface-conjugated RGD-peptide to Modulate Binding of Liposomes to Activated Platelets

Platelet adhesion, activation and fibrinogen-mediated aggregation are primary events in vascular thrombosis and occlusion. An injectable delivery system that can carry thrombolytics selectively to the sites of active platelet aggregation has immense potential in minimally invasive targeted therapy o...

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Detalhes bibliográficos
Main Authors: Huang, Guofeng, Zhou, Zhongmin, Srinivasan, Rekha, Penn, Marc S, Kottke-Marchant, Kandice, Marchant, Roger E., Gupta, Anirban Sen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278119/
https://ncbi.nlm.nih.gov/pubmed/18192005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2007.12.015
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