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Efficient Control of Population Structure in Model Organism Association Mapping

Genomewide association mapping in model organisms such as inbred mouse strains is a promising approach for the identification of risk factors related to human diseases. However, genetic association studies in inbred model organisms are confronted by the problem of complex population structure among...

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Detalhes bibliográficos
Main Authors: Kang, Hyun Min, Zaitlen, Noah A., Wade, Claire M., Kirby, Andrew, Heckerman, David, Daly, Mark J., Eskin, Eleazar
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278096/
https://ncbi.nlm.nih.gov/pubmed/18385116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.080101
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