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Independent Effects of cis- and trans-regulatory Variation on Gene Expression in Drosophila melanogaster

Biochemical interactions between cis-regulatory DNA sequences and trans-regulatory gene products suggest that cis- and trans-acting polymorphisms may interact genetically. Here we present a strategy to test this hypothesis by comparing the relative cis-regulatory activity of two alleles in different...

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Détails bibliographiques
Auteurs principaux: Wittkopp, Patricia J., Haerum, Belinda K., Clark, Andrew G.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278090/
https://ncbi.nlm.nih.gov/pubmed/18245838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.082032
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