Effects of Selective Modulation of the Central Melanocortin-3-Receptor on Food Intake and Hypothalamic POMC Expression

Hypothalamic POMC neurons regulate energy balance via interactions with brain melanocortin receptors (MC-Rs). POMC neurons express the MC3-R which can function as an inhibitory autoreceptor in vitro. We now demonstrate that central activation of MC3-R with icv infusion of the specific MC3-R agonist,...

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Hoofdauteurs: Lee, Michelle, Kim, Andrea, Conwell, Irene M., Hruby, Victor, Mayorov, Alexander, Cai, Minying, Wardlaw, Sharon L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278043/
https://ncbi.nlm.nih.gov/pubmed/18155809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2007.11.005
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