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Selective knockdown of AT(1) receptors by RNA interference inhibits Val(5)-ANG II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells

Receptor-mediated endocytosis of extracellular ANG II has been suggested to play an important role in the regulation of proximal tubule cell (PTC) function. Using immortalized rabbit PTCs as an in vitro cell culture model, we tested the hypothesis that extracellular ANG II is taken up by PTCs throug...

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Autori principali: Li, Xiao C., Zhuo, Jia L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277517/
https://ncbi.nlm.nih.gov/pubmed/17428839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00463.2006
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