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Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial

BACKGROUND: Surgical resection alone is regarded as the standard of care for patients with liver metastases from colorectal cancer, but relapse is common. We assessed the combination of perioperative chemotherapy and surgery compared with surgery alone for patients with initially resectable liver me...

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Huvudupphovsmän: Nordlinger, Bernard, Sorbye, Halfdan, Glimelius, Bengt, Poston, Graeme J, Schlag, Peter M, Rougier, Philippe, Bechstein, Wolf O, Primrose, John N, Walpole, Euan T, Finch-Jones, Meg, Jaeck, Daniel, Mirza, Darius, Parks, Rowan W, Collette, Laurence, Praet, Michel, Bethe, Ullrich, Van Cutsem, Eric, Scheithauer, Werner, Gruenberger, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Lancet Publishing Group 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277487/
https://ncbi.nlm.nih.gov/pubmed/18358928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(08)60455-9
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