Development of Chronic Bronchitis and Emphysema in β-Epithelial Na(+) Channel–Overexpressing Mice

Rationale: Chronic obstructive pulmonary disease is a leading cause of death worldwide, but its pathogenesis is not well understood. Previous studies have shown that airway surface dehydration in β-epithelial Na(+) channel (βENaC)–overexpressing mice caused a chronic lung disease with high neonatal...

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Detalhes bibliográficos
Main Authors: Mall, Marcus A., Harkema, Jack R., Trojanek, Joanna B., Treis, Diana, Livraghi, Alessandra, Schubert, Susanne, Zhou, Zhe, Kreda, Silvia M., Tilley, Stephen L., Hudson, Elizabeth J., O'Neal, Wanda K., Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
C. Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277210/
https://ncbi.nlm.nih.gov/pubmed/18079494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200708-1233OC
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