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The aromatic cluster in KCHIP1b affects Kv4 inactivation gating
The KChIP1b splice variant has been shown to induce slow recovery from inactivation for Kv4.2 whereas KChIP1a enhanced the recovery. Both splice variants differ only by the insertion of the exon1b, rich in aromatic residues (5/11). We analysed in detail the modifications of Kv4.2 gating induced by t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2277206/ https://ncbi.nlm.nih.gov/pubmed/17640927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.139550 |
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