Indirect coupling between Ca(v)1.2 channels and ryanodine receptors to generate Ca(2+) sparks in murine arterial smooth muscle cells

In arterial vascular smooth muscle cells (VSMCs), Ca(2+) sparks stimulate nearby Ca(2+)-activated K(+) (BK) channels that hyperpolarize the membrane and close L-type Ca(2+) channels. We tested the contribution of L-type Ca(v)1.2 channels to Ca(2+) spark regulation in tibial and cerebral artery VSMCs...

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Main Authors: Essin, Kirill, Welling, Andrea, Hofmann, Franz, Luft, Friedrich C, Gollasch, Maik, Moosmang, Sven
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2007
主題:
Cardiovascular
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277062/
https://ncbi.nlm.nih.gov/pubmed/17673505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.138982
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