Imatinib mesylate, a new kid on the block for the treatment of anti-neutrophil cytoplasmic autoantibodies-associated vasculitis?

Persistent T cell activation is a common finding in anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated systemic vasculitis (AAV) patients. Because imatinib, a selective inhibitor of the ABL, ARG, PDGFR and c-KIT tyrosine kinases, inhibits T cell activation, this study was conducted to eval...

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Detalles Bibliográficos
Autores principales: Kälsch, A-I, Soboletzki, M, Schmitt, W H, van der Woude, F J, Hochhaus, A, Yard, B A, Birck, R
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2008
Materias:
Translational Studies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276962/
https://ncbi.nlm.nih.gov/pubmed/18190601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03572.x
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