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Human T cells stimulate fibroblast-mediated degradation of extracellular matrix in vitro

Several chronic diseases are characterized by inflammation, T cell recruitment and tissue remodelling. We hypothesized that activated T cells may stimulate remodelling of extracellular matrix (ECM) in vitro. Total T cells (CD3(+)) as well as CD4(+) and CD8(+) subsets were isolated from peripheral bl...

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Detalhes bibliográficos
Main Authors: Mikko, M, Fredriksson, K, Wahlström, J, Eriksson, P, Grunewald, J, Sköld, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276952/
https://ncbi.nlm.nih.gov/pubmed/18062794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03565.x
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