High serum YKL-40 level in a cohort of octogenarians is associated with increased risk of all-cause mortality

YKL-40 is secreted by macrophages, neutrophils, chondrocytes, endothelial-, vascular smooth muscle- and cancer cells. Interleukin (IL)-6 stimulates YKL-40 production in human in vivo studies. High serum YKL-40 is associated with poor prognosis in patients with inflammatory diseases and cancer. We st...

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Bibliographic Details
Main Authors: Johansen, J S, Pedersen, A N, Schroll, M, Jørgensen, T, Pedersen, B K, Bruunsgaard, H
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
Subjects:
Translational Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276948/
https://ncbi.nlm.nih.gov/pubmed/18070151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03561.x
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