l-Ficolin binding and lectin pathway activation by acetylated low-density lipoprotein

l-Ficolin, like mannan-binding lectin (MBL), is a lectin pathway activator present in normal human plasma. Upon binding ligand, l-ficolin similarly initiates C4 cleavage via the serine protease MBL-associated serine protease-2 (MASP-2). We sought further insight into l-ficolin binding reactions and...

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Bibliografiske detaljer
Main Authors: Faro, J, Chen, Y, Jhaveri, P, Oza, P, Spear, G T, Lint, T F, Gewurz, H
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2008
Fag:
Basic Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276939/
https://ncbi.nlm.nih.gov/pubmed/18031558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03538.x
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