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Natural human antibodies to pneumococcus have distinctive molecular characteristics and protect against pneumococcal disease

The molecular and functional characteristics of natural antibody from the preimmune repertoire have not been explored in detail in man. We describe seven human IgM monoclonal antibodies selected on the basis of pneumococcal polysaccharide binding that share both molecular and functional characterist...

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Detalhes bibliográficos
Main Authors: Baxendale, H E, Johnson, M, Stephens, R C M, Yuste, J, Klein, N, Brown, J S, Goldblatt, D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276916/
https://ncbi.nlm.nih.gov/pubmed/17983446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03535.x
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