Systemic vs. Central Administration of Common Hypnotics Reveals Opposing Effects on Genioglossus Muscle Activity in Rats

STUDY OBJECTIVES: To determine if systemic administration of selected sedative-hypnotics that modulate the function of the γ-amino-butyric acid-A (GABA(A)) receptor can: (i) delay arousal thereby allowing genioglossus (GG) activity to increase more in response to respiratory stimulation during sleep...

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Bibliographic Details
Main Authors: Park, Eileen, Younes, Magdy, Liu, Hattie, Liu, Xia, Horner, Richard L
Format: Artigo
Language:Inglês
Published: Associated Professional Sleep Societies, LLC 2008
Subjects:
Hypnotics and Genioglossus Activity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276746/
https://ncbi.nlm.nih.gov/pubmed/18363312
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