Cleavage of Myelin Associated Glycoprotein by Matrix Metalloproteinases

Derivative myelin associated glycoprotein (dMAG) results from proteolysis of transmembrane MAG and can inhibit axonal growth. We have tested the ability of certain matrix metalloproteinases (MMPs) elevated with inflammatory and demyelinating diseases to cleave MAG. We show MMP-2, MMP-7 and MMP-9, bu...

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Detalhes bibliográficos
Main Authors: Milward, Elizabeth, Kim, Kee Jun, Szklarczyk, Arek, Nguyen, Thien, Melli, Giorgia, Nayak, Mamatha, Deshpande, Deepa, Fitzsimmons, Chantel, Hoke, Ahmet, Kerr, Douglas, Griffin, John W., Calabresi, Peter A., Conant, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276728/
https://ncbi.nlm.nih.gov/pubmed/18063113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.11.001
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