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Kisspeptin Acts Directly and Indirectly to Increase Gonadotropin-Releasing Hormone Neuron Activity and Its Effects Are Modulated by Estradiol

GnRH neurons play a pivotal role in the central regulation of fertility. Kisspeptin greatly increases GnRH/LH release and GnRH neuron firing activity and may be involved in estradiol feedback, but the neurobiological mechanisms for these actions are unknown. G protein-coupled receptor 54, the recept...

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Библиографические подробности
Главные авторы: Pielecka-Fortuna, Justyna, Chu, Zhiguo, Moenter, Suzanne M.
Формат: Artigo
Язык:Inglês
Опубликовано: The Endocrine Society 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276721/
https://ncbi.nlm.nih.gov/pubmed/18162521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1365
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