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Mechanism of Action of l-CDB-4022, a Potential Nonhormonal Male Contraceptive, in the Seminiferous Epithelium of the Rat Testis

The present study was conducted to elucidate the possible molecular mechanisms involved in the antispermatogenic activity of l-CDB-4022, an indenopyridine. In this study 45-d-old male Sprague-Dawley rats were treated with a single oral dose of l-CDB-4022 (2.5 mg/kg) or vehicle, and blood and testes...

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Autors principals: Koduri, Sailaja, Hild, Sheri Ann, Pessaint, Laurent, Reel, Jerry R., Attardi, Barbara J.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276710/
https://ncbi.nlm.nih.gov/pubmed/18174280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1332
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