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Layer selective presynaptic modulation of excitatory inputs to hippocampal CA1 by μ-opioid receptor activation

Chronic and acute activation of μ-opioid receptors (MOR) in hippocampal CA1 disrupts rhythmic activity, alters activity-dependent synaptic plasticity and impairs spatial memory formation. In CA1, MORs act by hyperpolarizing inhibitory interneurons and suppressing inhibitory synaptic transmission. MO...

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Bibliografiske detaljer
Hovedforfatter: McQuiston, A. Rory
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276608/
https://ncbi.nlm.nih.gov/pubmed/18065149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.09.077
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