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Fast dynamics perturbation analysis for prediction of protein functional sites

BACKGROUND: We present a fast version of the dynamics perturbation analysis (DPA) algorithm to predict functional sites in protein structures. The original DPA algorithm finds regions in proteins where interactions cause a large change in the protein conformational distribution, as measured using th...

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Bibliografiske detaljer
Main Authors: Ming, Dengming, Cohn, Judith D, Wall, Michael E
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276503/
https://ncbi.nlm.nih.gov/pubmed/18234095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-5
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