Blockade of Endothelinergic Receptors Prevents Development of Proliferative Vitreoretinopathy in Mice

Proliferative vitreoretinopathy (PVR) is characterized by severe glial remodeling. Glial activation and proliferation that occur in brain diseases are modulated by endothelin-1 (ET-1) and its receptor B (ETR-B). Because retinal astrocytes contain ET-1 and express ETR-B, we studied the changes of the...

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Detalhes bibliográficos
Main Authors: Iribarne, María, Ogawa, Liliana, Torbidoni, Vanesa, Dodds, Cristian M., Dodds, Ricardo A., Suburo, Angela M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276418/
https://ncbi.nlm.nih.gov/pubmed/18310504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070605
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