Regulation of Arterial-Venous Differences in Tumor Necrosis Factor Responsiveness of Endothelial Cells by Anatomic Context

We analyzed tumor necrosis factor (TNF) responses of human umbilical artery and vein endothelial cells (HUAECs and HUVECs) in organ and cell culture. In organ culture, TNF induced expression of E-selectin, VCAM-1, and ICAM-1 on HUVECs but only ICAM-1 on HUAECs. Activation of nuclear factor-κB, c-jun...

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Main Authors: Liu, Meng, Kluger, Martin S., D’Alessio, Alessio, García-Cardeña, Guillermo, Pober, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276407/
https://ncbi.nlm.nih.gov/pubmed/18292233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070603
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