Inactivation of [Fe-S] Metalloproteins Mediates Nitric Oxide-Dependent Killing of Burkholderia mallei

BACKGROUND: Much remains to be known about the mechanisms by which O(2)-dependent host defenses mediate broad antimicrobial activity. METHODOLOGY/PRINCIPAL FINDINGS: We show herein that reactive nitrogen species (RNS) generated by inducible nitric oxide (NO) synthase (iNOS) account for the anti-Burk...

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Detalhes bibliográficos
Main Authors: Jones-Carson, Jessica, Laughlin, James, Hamad, Mohammed A., Stewart, Amanda L., Voskuil, Martin I., Vázquez-Torres, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276317/
https://ncbi.nlm.nih.gov/pubmed/18398486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001976
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