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Quantitative Analysis of the Efficiency of Clonal Deletion in the Thymus
One of the major mechanisms for establishing self-tolerance is the clonal deletion of self-reactive T cells during their development in the thymus. Using a TCR transgenic mouse model, we have established a quantitative ex vivo assay for examining the sensitivity and specificity of negative selection...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
1994
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275944/ https://ncbi.nlm.nih.gov/pubmed/7620325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1994/92025 |
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