Induction of Apoptosis in Thymocytes by Prostaglandin E(2) In Vivo

In vivo administration in mice of a synthetic analog of prostaglandin E(2) (PGE(2)) caused a selective and dramatic decrease of CD4(+)CD8(+) double-positive, CD3/T-cell-receptor-αb(10) cells in the thymus. This loss was corticosteroid-independent and not affected by Cyclosporin A. The disappearance...

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Bibliografiske detaljer
Main Authors: Mastino, Antonio, Piacentini, Mauro, Grelli, Sandro, Favalli, Cartesio, Autuori, Francesco, Tentori, Lucio, Oliverio, Serafina, Garach, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275867/
https://ncbi.nlm.nih.gov/pubmed/1364176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1992/80863
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