Molecular and Cellular Basis of Microvascular Perfusion Deficits Induced by Clostridium perfringens and Clostridium septicum

Reduced tissue perfusion leading to tissue ischemia is a central component of the pathogenesis of myonecrosis caused by Clostridium perfringens. The C. perfringens α-toxin has been shown capable of inducing these changes, but its potential synergy with perfringolysin O (θ-toxin) is less well underst...

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Detalhes bibliográficos
Main Authors: Hickey, Michael J., Kwan, Rain Y. Q., Awad, Milena M., Kennedy, Catherine L., Young, Lauren F., Hall, Pam, Cordner, Leanne M., Lyras, Dena, Emmins, John J., Rood, Julian I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275794/
https://ncbi.nlm.nih.gov/pubmed/18404211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000045
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