Sequence variation in the human transcription factor gene POU5F1

BACKGROUND: POU5F1 expression is required to maintain stem cell pluripotency and for primordial germ cells to retain proliferative capability in embryonic development. Recent evidence suggests that POU5F1 may also be a testicular germ cell carcinoma (TGCC) oncogene, and POU5F1 variation may influenc...

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Detalhes bibliográficos
Main Authors: Hussain, Shehnaz K, Sequerra, Reynaldo, Bertucci, Caterina, Hastings, Noel C, Rieder, Mark, Schwartz, Stephen M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275747/
https://ncbi.nlm.nih.gov/pubmed/18254969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-15
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