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Mechanosensitive Membrane Channels in Action
The tension-driven gating process of MscL from Mycobacterium tuberculosis, Tb-MscL, has been addressed at near-atomic detail using coarse-grained molecular dynamics simulations. To perform the simulations, a novel coarse-grained peptide model based on a thermodynamic parameterization of the amino-ac...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275678/ https://ncbi.nlm.nih.gov/pubmed/18192351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.119966 |
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