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Mechanosensitive Membrane Channels in Action

The tension-driven gating process of MscL from Mycobacterium tuberculosis, Tb-MscL, has been addressed at near-atomic detail using coarse-grained molecular dynamics simulations. To perform the simulations, a novel coarse-grained peptide model based on a thermodynamic parameterization of the amino-ac...

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Main Authors: Yefimov, Serge, van der Giessen, Erik, Onck, Patrick R., Marrink, Siewert J.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275678/
https://ncbi.nlm.nih.gov/pubmed/18192351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.119966
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