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Targeting of beta-glucuronidase to lysosomes in mannose 6-phosphate receptor-deficient MOPC 315 cells

The murine plasma cell line MOPC 315 efficiently targets newly synthesized acid hydrolases to lysosomes in spite of a marked deficiency in the level of the mannose 6-phosphate receptor (Gabel, C., D. Goldberg, and S. Kornfeld, 1983, Proc. Natl. Acad. Sci. USA, 80:775- 779). To better understand the...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275628/
https://ncbi.nlm.nih.gov/pubmed/6330127
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