Clinical outcome and prognostic factors for patients treated within the context of a phase I study: the Royal Marsden Hospital experience

The main aim of phase I trials is to evaluate the tolerability and pharmacology of a new compound. However, investigating the potential for clinical benefit is also a key objective. Our phase I trial portfolio incorporates a range of new drugs, including molecular targeted agents, sometimes given to...

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Main Authors: Arkenau, H-T, Olmos, D, Ang, J E, de Bono, J, Judson, I, Kaye, S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
Teme:
Clinical Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275488/
https://ncbi.nlm.nih.gov/pubmed/18349817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604218
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