ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries

BACKGROUND AND PURPOSE: ZP120 (Ac-RYYRWKKKKKKK-NH(2)), is a new partial nociceptin/orphanin FQ (NOP) receptor agonist with sodium-potassium sparing aquaretic effects. The mechanisms of vasodilatation of ZP120 were examined in rat mesenteric resistance arteries. EXPERIMENTAL APPROACH: Arterial segmen...

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Autores principales: Simonsen, U, Laursen, B E, Petersen, J S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275454/
https://ncbi.nlm.nih.gov/pubmed/18193068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707688
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