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Colchicine suppresses neutrophil superoxide production in a murine model of gouty arthritis: a rationale for use of low-dose colchicine

Background and purpose: When used to treat gouty arthritis, colchicine is believed to work by inhibiting microtubule-dependent cell infiltration. However, in vitro, colchicine also reduces monosodium urate (MSU)-induced superoxide production by neutrophils. Our study aimed to compare the effects of...

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Detalhes bibliográficos
Main Authors: Chia, E W, Grainger, R, Harper, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275448/
https://ncbi.nlm.nih.gov/pubmed/18264123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.20
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