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Enhanced nitric oxide and cyclic GMP formation plays a role in the anti-platelet activity of simvastatin
BACKGROUND AND PURPOSE: It has been found that 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) exert various vascular protective effects, beyond their cholesterol-lowering property, including inhibition of platelet-dependent thrombus formation. The objective of the pr...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275444/ https://ncbi.nlm.nih.gov/pubmed/18264124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.19 |
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